St. Clair, Missouri – Route 66 Town Profile
Three Alignments, One Legendary Stop
St. Clair, Missouri sits in Franklin County along three different Route 66 alignments, making it a layered destination for travelers seeking authentic Mother Road nostalgia.
Route 66 Highlights
Hot & Cold Water Towers
The labels “HOT” and “COLD” are purely humorous—both towers hold regular water.
Meramec Caverns Barn Signs
Roadside painted barn advertising for Meramec Caverns in Stanton, MO.
Welcome Sign
A warm and iconic greeting for travelers on the Mother Road.
Historic Route 66 byway marker
Classic emblem marking the legendary Mother Road.
Keep Riding
- Top Route 66 Towns to Visit in Missouri → St. Louis → St. Clair → Cuba → Rolla → Devil's Elbow → Lebanon → Springfield → Joplin
- Missouri State Guide →
- View Itineraries → Route 66 - The Ultimate Guide
Ready to hit the Mother Road?
Pick your itinerary, fuel up, and start your Route 66 adventure today.